The Autoimmune Registry
Autoimmune neutropenia Graphs for this disease are generated based on data from the Autoimmune Registry Inc.
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  • Names
    • Autoimmune neutropenia
    • Autoimmune neutropenia of infancy
    • Primary autoimmune neutropenia

    Category: Blood
    Prevalence 1,666 cases in the US (Chaudhari 2020). Female/Male ratio: 14.0x.
    Age of Onset Present at birth.
    Description Neutropenia is defined as a low white blood cell count. There are many forms of neutropenia connected to autoimmune disease. It is important to understand which form is which.

    Primary neutropenia is diagnosed when there are no other conditions diagnosed. Secondary neutropenia is a low white blood cell count that occurs when other diseases are present, such as lupus, rheumatoid arthritis, or inflammatory bowel disease. This article only covers primary neutropenia.

    Primary neutropenia most often appears in infants and children. The cause may be unrelated to autoimmune disease. Most cases of childhood primary neutropenia that are autoimmune are not serious and the disease goes away in 3 to 5 years with no long term effects. However, in a relatively small number of patients, the disease becomes chronic. Adults, mostly women, can also develop primary autoimmune neutropenia after childhood. These cases are almost always chronic.

    In chronic autoimmune neutropenia the body produces IgG antibodies that target and destroy the body's own white blood cells (“neutrophils”), which leads to a lowered white blood cell count and leaves patients with weakened immune systems susceptible to bacterial and other infections.


    Evidence of autoimmunity: Antibody
    Patient Groups
    Bloggers
      Symptoms
      Resources Link to Clinical Trials
      Link to PubMed
      References Link to Cleveland Clinic
      Link to Healthline
      Profile by: Darrison Haftarczyk
    • Profile updated September 2024
    • Charts generated Nov 16, 2024 at 09:55 AM ET
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      Autoimmune neutropenia sex breakdown


      Autoimmune neutropenia age breakdown

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      Graphs for this disease are generated based on data from the Autoimmune Registry Inc.

    • Autoimmune neutropenia top comorbidities/symptoms
      Chart is omitted due to low report count.

      Autoimmune neutropenia top autoimmune comorbidities


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      * Disease is suspected as autoimmune, but unconfirmed.
      Data Source: Graphs on this page represent data from the Autoimmune Registry Inc. here. To protect participant anonymity, results derived from fewer than 5 participants are not graphed. The Autoimmune Registry Inc is a 501(c)(3) non-profit supported by donors like you.

    • Anti-inflammatory / specialty medications and supplements


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      * Biologic medications.
      Data Source: Graphs on this page represent data in electronic health records from the All of Us research database. As of July 2024, there are 451,000 sets of electronic health records collected from participants. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

    • Quick links: 
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      Patient-reported 7-day average pain
      Chart is omitted due to low report count.


      Patient-reported 7-day average fatigue
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      General physical health
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      General mental health
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      Social and relationship satisfaction
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      General quality of life
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      Ability to carry out social roles and activities
      Chart is omitted due to low report count.


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      Data Source: Graphs on this page represent data in self-reported survey results from the All of Us research database. As of July 2024, there are 560,000 participants who have completed these surveys. This dataset, however, may not be representative of the US population. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

    • Quick links: 
      Quick Links

      Concerns about ability to pay
      Chart is omitted due to low report count.


      Feeling unheard by healthcare providers
      Chart is omitted due to low report count.


      Patient employment status
      Chart is omitted due to low report count.


      Patient insurance coverage
      Chart is omitted due to low report count.


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      Graphs for this disease are generated based on data from the Autoimmune Registry Inc.