The Autoimmune Registry
Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection Graphs for this disease are generated based on data from the Autoimmune Registry Inc.
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  • Names
    • Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection
    • Pediatric Acute-onset Neuropsychiatric Syndrome
    Abbreviations: PANDAS, PANS
    Category: Nervous System
    Prevalence 370,000 cases in the US. No studies found. Female/Male ratio: 6.0x.
    Age of Onset Onset typically occurs between ages 3 and 12.
    Description Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus (PANDAS) affect children, adolescents, and young adults who may present with acute onset of obsessive-compulsive disorder (OCD) and/or tics following strep infection. PANDAS is a subset of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) in which similar symptoms result from a misguided immune response following other infectious or environmental triggers such as the flu, COVID, or tick-borne diseases.

    Evidence of autoimmunity: Antibody Suspected
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      Resources Link to Clinical Trials
      Link to PubMed
      References Link to Healthline
      Link to Cleveland Clinic
      Profile by: Angela Ebejer
    • Profile updated September 2024
    • Charts generated Nov 16, 2024 at 09:55 AM ET
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      Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection sex breakdown


      Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection age breakdown

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      Graphs for this disease are generated based on data from the Autoimmune Registry Inc.

    • Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection top autoimmune comorbidities


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      * Disease is suspected as autoimmune, but unconfirmed.
      Data Source: Graphs on this page represent data from the Autoimmune Registry Inc. here. To protect participant anonymity, results derived from fewer than 5 participants are not graphed. The Autoimmune Registry Inc is a 501(c)(3) non-profit supported by donors like you.


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      * Biologic medications.
      Data Source: Graphs on this page represent data in electronic health records from the All of Us research database. As of July 2024, there are 451,000 sets of electronic health records collected from participants. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

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      Data Source: Graphs on this page represent data in self-reported survey results from the All of Us research database. As of July 2024, there are 560,000 participants who have completed these surveys. This dataset, however, may not be representative of the US population. A snapshot of the data can be found here. To protect participant anonymity, results derived from fewer than 20 participants are not graphed.
      The All of Us Research Program is supported by the National Institutes of Health, Office of the Director: Regional Medical Centers: 1 OT2 OD026549; 1 OT2 OD026554; 1 OT2 OD026557; 1 OT2 OD026556; 1 OT2 OD026550; 1 OT2 OD 026552; 1 OT2 OD026553; 1 OT2 OD026548; 1 OT2 OD026551; 1 OT2 OD026555; IAA #: AOD 16037; Federally Qualified Health Centers: HHSN 263201600085U; Data and Research Center: 5 U2C OD023196; Biobank: 1 U24 OD023121; The Participant Center: U24 OD023176; Participant Technology Systems Center: 1 U24 OD023163; Communications and Engagement: 3 OT2 OD023205; 3 OT2 OD023206; and Community Partners: 1 OT2 OD025277; 3 OT2 OD025315; 1 OT2 OD025337; 1 OT2 OD025276. In addition, the All of Us Research Program would not be possible without the partnership of its participants.

    • Quick links: 
      Quick Links

      Join the registry!

      Graphs for this disease are generated based on data from the Autoimmune Registry Inc.